^ First, find a decent sprite website. The greatest Mario sprite site of all time is
www.mfgg.net. The Mario content is at least 300 times that of the spriters resource.
Anyway, when you reach the sprites on the internet, right click and press copy. Paste it on Paint. Find more sprites and paste it. Eventually, you should stop. Save and give it a name, such as "Kirby Lib".
Don't forget the backgrounds, so that it could look like the level of a game. If you go to MFGG and search "Black Squirrel", you will find his sprites. He has a good selection of backgrounds for you to use. Get some backrounds and save it onto a new paint browser.
Now that you're ready with your sprites, open a new browser. Take the "square" tool and make a large square. Customize a simple backround and fit it into the square. Use the "copy" tool to copy this backround and put it next to the first. Do this as many times as you want, but it should be an even number. Carry half of it(using the copy tool) and put it directly under the top half. Now you have frames.
Then take your character sprites and put copy them off of your lib and paste them onto your comic. Bring them over to the backround so that it is stepping onto the ground. Use various animations to show what he's doing. Use your frames, which can be very limited in a short, to make jokes, if you're good at it.
The most important tool in making a joke, or a comic in general, is to use dialogue. Use the dialogue tool to make funny jokes, like in Mario Bros. the comic, which you should check out.
I'm good at making comics, and though I'm not experienced like Jay and Sean, you can make decent comics on your first try if you put effort into it.